Exploring how mind-body approaches can reduce symptom burden and improve quality of life
Written by Dr. Antonia Repollet
Licensed Clinical Psychologist
Certified School Psychologist
GI Psychology
When you live with inflammatory bowel disease (IBD)—like Crohn’s disease or ulcerative colitis—you get used to hearing about colonoscopies, labs, and medications. But what if one of the most helpful tools isn’t just aimed at your gut—but also at your brain?
Enter gut-directed hypnotherapy! A mind-body approach designed to calm the digestive system by changing how the brain and gut communicate.
Originally developed for conditions like irritable bowel syndrome (IBS), gut-directed hypnosis is now gaining attention in the IBD world too. And for good reason.

What is Gut-Directed Hypnotherapy?
Gut-directed hypnotherapy is a structured form of clinical hypnosis. Sessions typically involve a trained clinician guiding you into a relaxed state using visualizations and focused suggestions, many of which target the gut’s motility, sensitivity, and immune response.
You’re not unconscious or out of control during hypnosis. Instead, it’s a calm, focused state where your mind becomes more responsive to helpful suggestions, especially those aimed at regulating discomfort and calming the nervous system. Think of it like giving your digestive system a guided meditation, written just for its needs.
Why Try Gut-directed Hypnotherapy for IBD?
The gut and brain are deeply connected through the gut-brain axis, which includes the vagus nerve, IBD is a structural disease involving inflammation in the digestive tract; therefore, of course gut-directed hypnotherapy won’t replace your medical treatment. But, when used alongside traditional care, it can help in powerful ways.
Research shows that GDH can:
- Lower stress and anxiety, which are common triggers for IBD flares
- Modulate gut sensitivity and the brain-gut stress response
- Improve sleep and quality of life, especially during remission or post-flare recovery
- Enhance resilience in coping with ongoing symptoms like urgency, bloating, or abdominal pain
In fact, one study found that patients with ulcerative colitis who used gut-directed hypnosis had longer periods of remission and fewer flares compared to those receiving standard care alone (Keefer et al., 2013).
Another study linked hypnosis to reductions in inflammatory markers during flare-ups, suggesting that mind-body therapy may help regulate immune response as well (Mawdsley et al., 2008).
How It Works: Brain-Gut Pathways
The gut and brain talk constantly via the vagus nerve and a system of chemical messengers. In IBD, this communication can become dysregulated, especially during times of stress, anxiety, or poor sleep.
Hypnotherapy helps rebalance this system by targeting:
- The enteric nervous system (your “second brain” in the gut)
- The central nervous system, especially threat perception
- And the immune response, which can amplify symptoms when the brain interprets the gut as unsafe
When your body feels safe, it functions differently—and that includes digestion and inflammation.
What Happens in a Gut-Directed Hypnotherapy Session?
Gut-directed hypnotherapy is delivered by a licensed professional trained in clinical hypnosis for GI disorders. Sessions may include:
- Imagery of soothing natural settings (e.g., a warm beach or mountain cabin)
- Suggestions for things such as intestinal healing, regulation, and ease
- Anchoring techniques to calm the body (like placing a hand on the belly or chest)
- Personal metaphors (like a thermostat turning down discomfort)
- And audio recordings for between-session home practice
It’s tailored to your symptoms and personality—not a one-size-fits-all script.
Is It Right for You?
Gut-directed hypnotherapy may be a good fit if:
- You’re in remission or experiencing mild to moderate symptoms
- You’re dealing with symptoms that linger even when inflammation is under control
- You notice a pattern of flares following stress, sleep loss, or emotional distress
- You want to feel more in control and connected to your body (not at odds with it)
It’s also helpful for those navigating medical trauma, medical procedure anxiety, or post-flare emotional recovery, which are often overlooked in IBD treatment.
Final Thoughts
Gut-directed hypnotherapy won’t replace your IBD medication or your GI team—but it might help you feel like more than just a patient in survival mode. It’s a gentle, evidence-based tool that supports both symptom relief and deeper emotional resilience.
If you’re curious, talk to a gastropsychologist or gut-brain therapist trained in gut-directed hypnotherapy. After all, your gut has a story, and sometimes it’s worth listening to it in a new way.
Looking for relief from these symptoms? Our 8-week virtual IBD Psychotherapy Group, where adults with Crohn’s and colitis can learn evidence-based tools to manage stress and symptoms. Enroll today!
Further Reading
- GI Psychology
- Crohn’s & Colitis Foundation
- Rome Foundation
- International Foundation for Gastrointestinal Disorders
References
Keefer, L., Taft, T. H., Kiebles, J. L., Martinovich, Z., Barrett, T. A., & Palsson, O. S. (2013). Gut-directed hypnotherapy significantly augments clinical remission in quiescent ulcerative colitis. Alimentary pharmacology & therapeutics, 38(7), 761–771.
Mawdsley, J. E., Jenkins, D. G., Macey, M. G., Langmead, L., & Rampton, D. S. (2008). The effect of hypnosis on systemic and rectal mucosal measures of inflammation in ulcerative colitis. The American journal of gastroenterology, 103(6), 1460–1469.
